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SS-31, also known as Elamipretide, is a mitochondria-targeted tetrapeptide that improves mitochondrial function and is currently undergoing clinical trials for various diseases, including heart failure and mitochondrial myopathy.
It interacts with cardiolipin, a phospholipid abundant in the inner mitochondrial membrane, and enhances electron transfer, ATP synthesis, and reduces reactive oxygen species (ROS) production.
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