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Prilocaine hcl powder cas 1786-81-8 is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.
Product introduction：
Cas: 1786-81-8
Other names: Prilocaine
MF: C13H21ClN2O
Molecular Weight: 256.77
Perform Standard: USP
Appearance: White crystalline powder, odorless, bitter taste
Loss on drying: ≤0.3%
Residue on ignition: ≤0.1％
Heavy metals: ≤0.002%
Assay: 99.0% ～101.0%
Usage: Prilocaine hcl powder cas 1786-81-8 is a local anesthetic of the amino amide type,it is often used in dentistry. Prilocaine hcl powder cas 1786-81-8 is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.
Application: Prilocaine hcl powder cas 1786-81-8 is the hydrochloride salt form of prilocaine, an intermediate-acting local anesthetic of the amide type chemically related to lidocaine. Prilocaine hcl powder cas 1786-81-8 binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. This leads to a stabilization of the neuronal membrane and inhibits depolarization and results in a reversible blockage of nerve impulse generation and propagation along nerve fibres and subsequent reversible loss of sensation.
Other chemical names: N-(2-methylphenyl)-2-(propylamino)propionamide, Prilocaine N-(2-Methylphenyl)-2-propylamino-propanamide, Astra 1512
Certificate of analysis
|
Item of Analysis |
Standard |
Result of Analysis |
|
Description |
White crystalline powder, odorless, bitter taste |
Complies
|
|
Freely soluble in water and in alcohol ， slightly soluble in chloroform，very slightly soluble in acetone，not soluble in ether |
Complies |
|
|
Melting Point |
166～169℃ |
167.1～168.8℃ |
|
Single impurity
|
≤0.2% |
0.01% |
|
Total impurity |
≤0.5% |
0.02% |
|
Relative Substances A
|
≤0.01% |
0.0039% |
|
Loss on drying
|
≤ 0.3% |
0.04% |
|
Residue on ignition
|
≤0.1％ |
0.08% |
|
Heavy metals
|
≤0.002% |
＜0.002% |
|
Residual solvents |
Should be to match with the standard |
Conforms |
|
Assay |
99.0% ～101.0% |
99.49% |
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